By Stefan H. E. Kaufmann, Bruce D. Walker
Supplying the newest details on preventive, diagnostic and healing features of tuberculosis and AIDS, this is often the single ebook to put an immense emphasis at the expanding coexistence of those life-threatening illnesses in individuals.
Edited by way of impressive scientists within the box, this prepared reference is split into 3 major sections protecting immunology and vaccination options, medications, and medical issues.
well timed analyzing for microbiologists, virologists, bacteriologists, immunologists, and pathophysiologists, in addition to for the pharmaceutical and biotechnological industries.
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Additional info for AIDS and Tuberculosis: A Deadly Liaison
13, 46–53. M. D. (2009) 28 29 30 31 32 33 Differential neutralization of HIV replication in autologous CD4 T cells by HIV-speciﬁc CTL. J. , 83 (7), 3138–3149. L. I. (2002) Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeﬁciency virus infection. Nat. , 8, 493–499. B. M. (1997) Antiviral pressure exerted by HIV-1-speciﬁc cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus. Nat. , 3, 205–211. R. E. (1997) Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection.
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After depletion of peripheral CD8 þ T-cells in four vaccinated animals during the chronic phase, an increase in virus replication was observed which supported the crucial role that CD8 þ T-cells play in viral control. One drawback in these ﬁndings was the fact that the authors identiﬁed evidence of recombinant viruses emerging in some of the vaccinated animals. Taking this into consideration, the conclusion can be drawn that attenuated virus vaccines will not play a key role in future vaccine developments.
AIDS and Tuberculosis: A Deadly Liaison by Stefan H. E. Kaufmann, Bruce D. Walker